[HTML][HTML] Tumor development and angiogenesis in adult brain tumor: glioblastoma

BK Ahir, HH Engelhard, SS Lakka - Molecular neurobiology, 2020 - Springer
… The best-known angiogenesis regulators in GBM progression … of matrix components and
enhances the synthesis of collagenglioma cell proliferation, differentiation, tumor angiogenesis, …

Assessment of vascularity in glioblastoma and its implications on patient outcomes

BG McGahan, BK Neilsen, DL Kelly… - Journal of neuro …, 2017 - Springer
… hypoxia by increasing angiogenesis and inducing apoptosis [… role in embryonic vascularization
and tumor angiogenesis [58]. … in GBM does not affect overall or progression free survival, …

EGFR and EGFRvIII promote angiogenesis and cell invasion in glioblastoma: combination therapies for an effective treatment

S Keller, MHH Schmidt - International journal of molecular sciences, 2017 - mdpi.com
… It is also known that EGF promotes tumor angiogenesis, cell … The purpose of this review is
to provide current knowledge … to tumor progression, angiogenesis, and invasion in various …

Type-I collagen/collagenase modulates the 3D structure and behavior of glioblastoma spheroid models

IR Calori, SR Alves, H Bi… - ACS Applied Bio Materials, 2022 - ACS Publications
Collagen, as a matrix component, plays an essential role in … leading to angiogenesis. (33)
Thus, the development of spheroid … for every stage of tumor advancement. Therefore, this work …

[HTML][HTML] The role of collagens in glioma: A narrative review

Y Wang, T Ichinose, M Nakada - Glioma, 2022 - journals.lww.com
… has shown that collagen I contribute to glioma progression. It … increase collagen IV expression
and upregulate angiogenic … invasion through the collagen matrix.[ 49 ] G protein-coupled …

[HTML][HTML] Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma

W Yin, H Zhu, J Tan, Z Xin, Q Zhou… - Cancer Cell …, 2021 - cancerci.biomedcentral.com
… To further explore the function of collagen genes in promoting glioma progression, we used
rarely studied COL3A1 as a further research object. The results showed that the knockdown …

Identification of COL6A1 as the Key Gene Associated with Antivascular Endothelial Growth Factor Therapy in Glioblastoma Multiforme

H Lin, Y Yang, C Hou, J Zheng, G Lv… - Genetic testing and …, 2021 - liebertpub.com
… These studies suggest that COL6A1 plays significant role in tumor progression. … and
expression of collagen inhibit tumor angiogenesis, but does not promote glioma invasion and …

Collagen and derivatives-based materials as substrates for the establishment of glioblastoma organoids

L Sun, Y Jiang, H Tan, R Liang - International Journal of Biological …, 2023 - Elsevier
tumor cells. By releasing different growth factors and cytokines, reactive astrocytes engage
with glioma cells and facilitate the advancement of tumors [… The exact function of angiogenic

Extracellular proteolysis in glioblastoma progression and therapeutics

A Quesnel, GS Karagiannis, PS Filippou - … Acta (BBA)-Reviews on Cancer, 2020 - Elsevier
… In addition, collagen is upregulated during glioma … a critical role in glioblastoma progression
and tumour invasion, … increase of angiogenesis at early stage of tumour progression during …

Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma cell number, invasion, and temozolomide resistance

MT Ngo, E Karvelis, BAC Harley - Integrative Biology, 2020 - academic.oup.com
… a novel role for TIMP1 in facilitating glioblastoma tumor cell … the role of angiocrine signals
in glioblastoma progression. … -angiogenic signaling to promote new capillary formation at the …